GO Annotations Graph

• Symbol: Litaf
• Name: LPS-induced TN factor
• ID: MGI:1929512

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:65663
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0050699	WW domain binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0098559	cytoplasmic side of early endosome membrane	ISO	J:164563
Cellular Component	GO:0098560	cytoplasmic side of late endosome membrane	ISO	J:164563
Cellular Component	GO:0098560	cytoplasmic side of late endosome membrane	IBA	J:265628
Cellular Component	GO:0098574	cytoplasmic side of lysosomal membrane	ISO	J:164563
Cellular Component	GO:0098574	cytoplasmic side of lysosomal membrane	IBA	J:265628
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:70137
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:113750
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	IMP	J:85146
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0001817	regulation of cytokine production	IBA	J:265628
Biological Process	GO:0010935	regulation of macrophage cytokine production	IMP	J:113750
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:180147