GO Annotations Graph

• Symbol: Ndfip1
• Name: Nedd4 family interacting protein 1
• ID: MGI:1929601

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:116617
Molecular Function	GO:0005515	protein binding	IPI	J:65663
Molecular Function	GO:0050699	WW domain binding	IBA	J:265628
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Molecular Function	GO:0050699	WW domain binding	IPI	J:75315
Cellular Component	GO:0005938	cell cortex	IDA	J:116617
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:75315
Cellular Component	GO:0000139	Golgi membrane	IC	J:75315
Cellular Component	GO:0000139	Golgi membrane	IC	J:75315
Cellular Component	GO:0016020	membrane	ISM	J:75315
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	IMP	J:116617
Biological Process	GO:0032633	interleukin-4 production	IMP	J:116617
Biological Process	GO:0006879	intracellular iron ion homeostasis	ISO	J:164563
Biological Process	GO:0030001	metal ion transport	IBA	J:265628
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	IMP	J:116617
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:116617
Biological Process	GO:0032713	negative regulation of interleukin-4 production	IMP	J:116617
Biological Process	GO:0048294	negative regulation of isotype switching to IgE isotypes	IMP	J:116617
Biological Process	GO:0051224	negative regulation of protein transport	ISO	J:164563
Biological Process	GO:0032410	negative regulation of transporter activity	ISO	J:164563
Biological Process	GO:0002829	negative regulation of type 2 immune response	IMP	J:116617
Biological Process	GO:0045732	positive regulation of protein catabolic process	IMP	J:116617
Biological Process	GO:0045732	positive regulation of protein catabolic process	IDA	J:116617
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IBA	J:265628
Biological Process	GO:0030163	protein catabolic process	IMP	J:116617
Biological Process	GO:0030163	protein catabolic process	IDA	J:116617
Biological Process	GO:0048302	regulation of isotype switching to IgG isotypes	IMP	J:116617
Biological Process	GO:0045619	regulation of lymphocyte differentiation	IMP	J:116617
Biological Process	GO:0002761	regulation of myeloid leukocyte differentiation	IMP	J:116617
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0007034	vacuolar transport	IEA	J:72247