GO Annotations Graph

• Symbol: Rsad2
• Name: radical S-adenosyl methionine domain containing 2
• ID: MGI:1929628

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	ISO	J:164563
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	IBA	J:265628
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:72247
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:185023
Molecular Function	GO:0005515	protein binding	IPI	J:169840
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:193971
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0005811	lipid droplet	IDA	J:169840
Cellular Component	GO:0005811	lipid droplet	IDA	J:186054
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Biological Process	GO:0035710	CD4-positive, alpha-beta T cell activation	IMP	J:148305
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	IMP	J:148305
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IDA	J:127942
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0050709	negative regulation of protein secretion	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	IMP	J:186142
Biological Process	GO:0001503	ossification	ISO	J:155856
Biological Process	GO:0050778	positive regulation of immune response	IBA	J:265628
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	IMP	J:148305
Biological Process	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	IMP	J:169840
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	IMP	J:169840
Biological Process	GO:0030278	regulation of ossification	ISO	J:155856
Biological Process	GO:0009615	response to virus	IMP	J:186142
Biological Process	GO:0009615	response to virus	ISO	J:164563