GO Annotations Graph

• Symbol: Rec8
• Name: REC8 meiotic recombination protein
• ID: MGI:1929645

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:277855
Molecular Function	GO:0005515	protein binding	IPI	J:84400
Molecular Function	GO:0005515	protein binding	IPI	J:84400
Molecular Function	GO:0005515	protein binding	IPI	J:84400
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0008278	cohesin complex	IBA	J:265628
Cellular Component	GO:0000793	condensed chromosome	IDA	J:183026
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:176168
Cellular Component	GO:0000779	condensed chromosome, centromeric region	IDA	J:130184
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:130184
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:211663
Cellular Component	GO:0000794	condensed nuclear chromosome	IDA	J:182264
Cellular Component	GO:0000776	kinetochore	IDA	J:138779
Cellular Component	GO:0000800	lateral element	IDA	J:98372
Cellular Component	GO:0000800	lateral element	IDA	J:294078
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:123677
Cellular Component	GO:0030893	meiotic cohesin complex	IDA	J:182264
Cellular Component	GO:0030893	meiotic cohesin complex	IDA	J:176168
Cellular Component	GO:0030893	meiotic cohesin complex	IDA	J:123677
Cellular Component	GO:0030893	meiotic cohesin complex	IDA	J:199766
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912355
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912362
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912423
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912449
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912468
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912506
Cellular Component	GO:0005634	nucleus	IDA	J:84400
Cellular Component	GO:0000795	synaptonemal complex	IDA	J:84400
Biological Process	GO:0007059	chromosome segregation	IEA	J:60000
Biological Process	GO:0006302	double-strand break repair	IBA	J:265628
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IGI	J:185266
Biological Process	GO:0009566	fertilization	IMP	J:185266
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:123677
Biological Process	GO:0007141	male meiosis I	IMP	J:123677
Biological Process	GO:0051321	meiotic cell cycle	IPI	J:84400
Biological Process	GO:0051177	meiotic sister chromatid cohesion	IBA	J:265628
Biological Process	GO:0001556	oocyte maturation	IGI	J:123677
Biological Process	GO:0001556	oocyte maturation	IMP	J:123677
Biological Process	GO:0072520	seminiferous tubule development	IGI	J:185266
Biological Process	GO:0007062	sister chromatid cohesion	IEA	J:72247
Biological Process	GO:0007286	spermatid development	IMP	J:123677
Biological Process	GO:0007130	synaptonemal complex assembly	IGI	J:185266
Biological Process	GO:0007130	synaptonemal complex assembly	IGI	J:209347
Biological Process	GO:0007130	synaptonemal complex assembly	IGI	J:209347