GO Annotations Graph

• Symbol: Terf2ip
• Name: telomeric repeat binding factor 2, interacting protein
• ID: MGI:1929871

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:163158
Molecular Function	GO:0005515	protein binding	IPI	J:158884
Molecular Function	GO:0042162	telomeric DNA binding	IDA	J:199000
Molecular Function	GO:0042162	telomeric DNA binding	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:199000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:228117
Cellular Component	GO:0000781	chromosome, telomeric region	IMP	J:165984
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:158884
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:105516
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:163158
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:201813
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0000783	nuclear telomere cap complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912355
Cellular Component	GO:0005634	nucleus	IDA	J:163158
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0070187	shelterin complex	ISO	J:164563
Cellular Component	GO:0070187	shelterin complex	IBA	J:265628
Biological Process	GO:0048239	negative regulation of DNA recombination at telomere	IMP	J:158884
Biological Process	GO:0048239	negative regulation of DNA recombination at telomere	IMP	J:165984
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0032205	negative regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:163158
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP	J:163158
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:1901985	positive regulation of protein acetylation	ISO	J:164563
Biological Process	GO:0032206	positive regulation of telomere maintenance	NAS	J:319993
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:165984
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	IMP	J:158884
Biological Process	GO:0032204	regulation of telomere maintenance	ISO	J:164563
Biological Process	GO:0016233	telomere capping	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	ISO	J:164563
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IMP	J:158884
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IMP	J:165984
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IBA	J:265628