GO Annotations Graph

• Symbol: Trpm7
• Name: transient receptor potential cation channel, subfamily M, member 7
• ID: MGI:1929996

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:105078
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005262	calcium channel activity	ISO	J:155856
Molecular Function	GO:0005262	calcium channel activity	IBA	J:265628
Molecular Function	GO:0005262	calcium channel activity	IDA	J:105078
Molecular Function	GO:0016301	kinase activity	IDA	J:105078
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005261	monoatomic cation channel activity	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0017022	myosin binding	IPI	J:105078
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:222132
Molecular Function	GO:0005515	protein binding	IPI	J:105078
Molecular Function	GO:0004672	protein kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:105078
Cellular Component	GO:0001726	ruffle	IDA	J:105078
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0043196	varicosity	ISO	J:155856
Biological Process	GO:0031032	actomyosin structure organization	IDA	J:105078
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IBA	J:265628
Biological Process	GO:0006816	calcium ion transport	IDA	J:105078
Biological Process	GO:0016340	calcium-dependent cell-matrix adhesion	IDA	J:105078
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	ISO	J:155856
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0098655	monoatomic cation transmembrane transport	IBA	J:265628
Biological Process	GO:0006812	monoatomic cation transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0070266	necroptotic process	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0012501	programmed cell death	IEA	J:60000
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:105078
Biological Process	GO:0006468	protein phosphorylation	IDA	J:105078
Biological Process	GO:0051262	protein tetramerization	IEA	J:72247
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247