GO Annotations Graph

• Symbol: Bhlhe22
• Name: basic helix-loop-helix family, member e22
• ID: MGI:1930001

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:182304
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:182304
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:182304
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:182304
Molecular Function	GO:0070888	E-box binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:182304
Molecular Function	GO:0005515	protein binding	IPI	J:182304
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:182304
Biological Process	GO:0035881	amacrine cell differentiation	IMP	J:119663
Biological Process	GO:0021960	anterior commissure morphogenesis	IMP	J:182304
Biological Process	GO:0061564	axon development	IBA	J:265628
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	IMP	J:182304
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	IMP	J:182304
Biological Process	GO:0021796	cerebral cortex regionalization	IMP	J:196080
Biological Process	GO:0021540	corpus callosum morphogenesis	IMP	J:182304
Biological Process	GO:0021540	corpus callosum morphogenesis	IMP	J:182304
Biological Process	GO:0021957	corticospinal tract morphogenesis	IMP	J:182304
Biological Process	GO:0021957	corticospinal tract morphogenesis	IMP	J:182304
Biological Process	GO:0021957	corticospinal tract morphogenesis	IGI	J:182304
Biological Process	GO:0097154	GABAergic neuron differentiation	IMP	J:119663
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:78916
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:182304
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0022008	neurogenesis	IEA	J:72247
Biological Process	GO:0048663	neuron fate commitment	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:119663
Biological Process	GO:0060040	retinal bipolar neuron differentiation	IMP	J:119663
Biological Process	GO:0007423	sensory organ development	IBA	J:265628