GO Annotations Graph

• Symbol: Trem1
• Name: triggering receptor expressed on myeloid cells 1
• ID: MGI:1930005

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140677	molecular function activator activity	ISO	J:164563
Molecular Function	GO:0140319	receptor decoy activity	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Molecular Function	GO:0030547	signaling receptor inhibitor activity	ISO	J:164563
Molecular Function	GO:0004888	transmembrane signaling receptor activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0002526	acute inflammatory response	IEA	J:72247
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0032602	chemokine production	IBA	J:265628
Biological Process	GO:0032602	chemokine production	IGI	J:194295
Biological Process	GO:0001816	cytokine production	IGI	J:194295
Biological Process	GO:0002367	cytokine production involved in immune response	IBA	J:265628
Biological Process	GO:0002367	cytokine production involved in immune response	IGI	J:194295
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0030593	neutrophil chemotaxis	IBA	J:265628
Biological Process	GO:0030593	neutrophil chemotaxis	IGI	J:194295
Biological Process	GO:0072672	neutrophil extravasation	IGI	J:194295
Biological Process	GO:1990266	neutrophil migration	IGI	J:194295
Biological Process	GO:0070945	neutrophil-mediated killing of gram-negative bacterium	IBA	J:265628
Biological Process	GO:0070945	neutrophil-mediated killing of gram-negative bacterium	IGI	J:194295
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	ISO	J:155856
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	ISO	J:155856