Symbol Name ID |
Ern1
endoplasmic reticulum to nucleus signalling 1 MGI:1930134 |
Category | GO ID | Classification Term | Evidence | Reference | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Molecular Function | GO:0043531 | ADP binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0005524 | ATP binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0003824 | catalytic activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0004519 | endonuclease activity | IDA | J:107824 | |||||||||
Molecular Function | GO:0019899 | enzyme binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0030544 | Hsp70 protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0051879 | Hsp90 protein binding | ISO | J:155856 | |||||||||
Molecular Function | GO:0051879 | Hsp90 protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016787 | hydrolase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0042802 | identical protein binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0016301 | kinase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0000287 | magnesium ion binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0046872 | metal ion binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0000166 | nucleotide binding | IEA | J:60000 | |||||||||
Molecular Function | GO:0005161 | platelet-derived growth factor receptor binding | ISO | J:164563 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:201886 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:147348 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:145150 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:136554 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:136554 | |||||||||
Molecular Function | GO:0005515 | protein binding | IPI | J:200442 | |||||||||
Molecular Function | GO:0042803 | protein homodimerization activity | IDA | J:255334 | |||||||||
Molecular Function | GO:0042803 | protein homodimerization activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004672 | protein kinase activity | IEA | J:72247 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | IDA | J:255334 | |||||||||
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0004521 | RNA endonuclease activity | ISO | J:164563 | |||||||||
Molecular Function | GO:0004521 | RNA endonuclease activity | IBA | J:265628 | |||||||||
Molecular Function | GO:0004521 | RNA endonuclease activity | IDA | J:255334 | |||||||||
Molecular Function | GO:0004521 | RNA endonuclease activity | IDA | J:95320 | |||||||||
Molecular Function | GO:0004540 | RNA nuclease activity | IEA | J:72247 | |||||||||
Molecular Function | GO:0016740 | transferase activity | IEA | J:60000 | |||||||||
Molecular Function | GO:0045182 | translation regulator activity | TAS | J:171795 | |||||||||
Molecular Function | GO:0051082 | unfolded protein binding | IBA | J:265628 | |||||||||
Cellular Component | GO:1990597 | AIP1-IRE1 complex | IPI | J:136554 | |||||||||
Cellular Component | GO:0005737 | cytoplasm | ISO | J:164563 | |||||||||
Cellular Component | GO:0005783 | endoplasmic reticulum | ISO | J:164563 | |||||||||
Cellular Component | GO:0005789 | endoplasmic reticulum membrane | ISO | J:164563 | |||||||||
Cellular Component | GO:0005789 | endoplasmic reticulum membrane | IDA | J:57921 | |||||||||
Cellular Component | GO:1990630 | IRE1-RACK1-PP2A complex | ISO | J:164563 | |||||||||
Cellular Component | GO:1990604 | IRE1-TRAF2-ASK1 complex | ISO | J:164563 | |||||||||
Cellular Component | GO:1990604 | IRE1-TRAF2-ASK1 complex | IBA | J:265628 | |||||||||
Cellular Component | GO:0016020 | membrane | IEA | J:60000 | |||||||||
Cellular Component | GO:0005739 | mitochondrion | IDA | J:192731 | |||||||||
Cellular Component | GO:0005637 | nuclear inner membrane | IDA | J:107824 | |||||||||
Biological Process | GO:0006915 | apoptotic process | IEA | J:60000 | |||||||||
Biological Process | GO:0071333 | cellular response to glucose stimulus | ISO | J:164563 | |||||||||
Biological Process | GO:0034620 | cellular response to unfolded protein | ISO | J:164563 | |||||||||
Biological Process | GO:0035924 | cellular response to vascular endothelial growth factor stimulus | ISO | J:164563 | |||||||||
Biological Process | GO:0030968 | endoplasmic reticulum unfolded protein response | TAS | J:171795 | |||||||||
Biological Process | GO:0030968 | endoplasmic reticulum unfolded protein response | IDA | J:95320 | |||||||||
Biological Process | GO:0030968 | endoplasmic reticulum unfolded protein response | IDA | J:62257 | |||||||||
Biological Process | GO:0030968 | endoplasmic reticulum unfolded protein response | IDA | J:70005 | |||||||||
Biological Process | GO:0001935 | endothelial cell proliferation | ISO | J:164563 | |||||||||
Biological Process | GO:1901142 | insulin metabolic process | ISO | J:164563 | |||||||||
Biological Process | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IMP | J:147348 | |||||||||
Biological Process | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IBA | J:265628 | |||||||||
Biological Process | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IDA | J:66969 | |||||||||
Biological Process | GO:0036498 | IRE1-mediated unfolded protein response | ISO | J:164563 | |||||||||
Biological Process | GO:0036498 | IRE1-mediated unfolded protein response | IDA | J:255334 | |||||||||
Biological Process | GO:0036498 | IRE1-mediated unfolded protein response | IBA | J:265628 | |||||||||
Biological Process | GO:0036498 | IRE1-mediated unfolded protein response | IDA | J:210646 | |||||||||
Biological Process | GO:0008152 | metabolic process | IEA | J:60000 | |||||||||
Biological Process | GO:0006379 | mRNA cleavage | IDA | J:255334 | |||||||||
Biological Process | GO:0098787 | mRNA cleavage involved in mRNA processing | ISO | J:164563 | |||||||||
Biological Process | GO:0006397 | mRNA processing | IEA | J:72247 | |||||||||
Biological Process | GO:0070054 | mRNA splicing, via endonucleolytic cleavage and ligation | ISO | J:164563 | |||||||||
Biological Process | GO:0017148 | negative regulation of translation | TAS | J:171795 | |||||||||
Biological Process | GO:0036289 | peptidyl-serine autophosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:1990579 | peptidyl-serine trans-autophosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0016310 | phosphorylation | IEA | J:60000 | |||||||||
Biological Process | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response | ISO | J:164563 | |||||||||
Biological Process | GO:1904294 | positive regulation of ERAD pathway | TAS | J:171795 | |||||||||
Biological Process | GO:0043507 | positive regulation of JUN kinase activity | IMP | J:132966 | |||||||||
Biological Process | GO:0043507 | positive regulation of JUN kinase activity | ISO | J:164563 | |||||||||
Biological Process | GO:0033120 | positive regulation of RNA splicing | IDA | J:255334 | |||||||||
Biological Process | GO:0033120 | positive regulation of RNA splicing | ISO | J:164563 | |||||||||
Biological Process | GO:1904707 | positive regulation of vascular associated smooth muscle cell proliferation | ISO | J:164563 | |||||||||
Biological Process | GO:0046777 | protein autophosphorylation | IDA | J:255334 | |||||||||
Biological Process | GO:0046777 | protein autophosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0046777 | protein autophosphorylation | IDA | J:70005 | |||||||||
Biological Process | GO:0006468 | protein phosphorylation | ISO | J:164563 | |||||||||
Biological Process | GO:0034976 | response to endoplasmic reticulum stress | ISO | J:164563 | |||||||||
Biological Process | GO:0006986 | response to unfolded protein | IEA | J:60000 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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