GO Annotations Graph

• Symbol: Pmaip1
• Name: phorbol-12-myristate-13-acetate-induced protein 1
• ID: MGI:1930146

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:116441
Molecular Function	GO:0005515	protein binding	IPI	J:248256
Molecular Function	GO:0005515	protein binding	IPI	J:114705
Molecular Function	GO:0005515	protein binding	IPI	J:163471
Molecular Function	GO:0005515	protein binding	IPI	J:168877
Cellular Component	GO:0097136	Bcl-2 family protein complex	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:62057
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:172883
Biological Process	GO:0006915	apoptotic process	ISO	J:73065
Biological Process	GO:0042149	cellular response to glucose starvation	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:85569
Biological Process	GO:0044346	fibroblast apoptotic process	IMP	J:86466
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:86466
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:85569
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IDA	J:62057
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:219625
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:85569
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	IDA	J:172883
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	IMP	J:86466
Biological Process	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IMP	J:86466
Biological Process	GO:0010907	positive regulation of glucose metabolic process	ISO	J:164563
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:98100
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	IMP	J:85569
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0010498	proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	RCA	J:84168
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	ISO	J:164563
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IDA	J:172883
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IMP	J:85569
Biological Process	GO:0043331	response to dsRNA	ISO	J:164563
Biological Process	GO:0009411	response to UV	IMP	J:85569
Biological Process	GO:0010165	response to X-ray	IMP	J:85569
Biological Process	GO:0043029	T cell homeostasis	IMP	J:136278