GO Annotations Graph

• Symbol: Krit1
• Name: KRIT1, ankyrin repeat containing
• ID: MGI:1930618

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030695	GTPase regulator activity	TAS	J:66990
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:169900
Molecular Function	GO:0005515	protein binding	IPI	J:146528
Molecular Function	GO:0005515	protein binding	IPI	J:187714
Molecular Function	GO:0005515	protein binding	IPI	J:191763
Molecular Function	GO:0005515	protein binding	IPI	J:187714
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:191763
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	IDA	J:146528
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0045454	cell redox homeostasis	ISO	J:164563
Biological Process	GO:0045454	cell redox homeostasis	IMP	J:163084
Biological Process	GO:0045454	cell redox homeostasis	IBA	J:265628
Biological Process	GO:0003158	endothelium development	NAS	J:320403
Biological Process	GO:0033622	integrin activation	ISO	J:164563
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:170021
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0016525	negative regulation of angiogenesis	IBA	J:265628
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0010596	negative regulation of endothelial cell migration	ISO	J:164563
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	IDA	J:146528
Biological Process	GO:0045765	regulation of angiogenesis	NAS	J:320403
Biological Process	GO:2000114	regulation of establishment of cell polarity	IMP	J:170050
Biological Process	GO:2000114	regulation of establishment of cell polarity	ISO	J:164563
Biological Process	GO:2000114	regulation of establishment of cell polarity	IBA	J:265628