GO Annotations Graph

• Symbol: Tesc
• Name: tescalcin
• ID: MGI:1930803

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IDA	J:114137
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0000287	magnesium ion binding	IDA	J:114137
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0019212	phosphatase inhibitor activity	IDA	J:114137
Molecular Function	GO:0019212	phosphatase inhibitor activity	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:114137
Molecular Function	GO:0004860	protein kinase inhibitor activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:148940
Cellular Component	GO:0005737	cytoplasm	IDA	J:114137
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:114137
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:114137
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0001726	ruffle	IDA	J:114137
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:164563
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:72689
Biological Process	GO:0008584	male gonad development	IEP	J:67267
Biological Process	GO:0030219	megakaryocyte differentiation	IEP	J:152658
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	ISO	J:164563
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	IBA	J:265628
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	ISO	J:164563
Biological Process	GO:0032417	positive regulation of sodium:proton antiporter activity	ISO	J:164563
Biological Process	GO:0032417	positive regulation of sodium:proton antiporter activity	IBA	J:265628
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IBA	J:265628
Biological Process	GO:0051604	protein maturation	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	IBA	J:265628