GO Annotations Graph

• Symbol: Noc2l
• Name: NOC2 like nucleolar associated transcriptional repressor
• ID: MGI:1931051

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042393	histone binding	ISA	J:103923
Molecular Function	GO:0042393	histone binding	ISA	J:103923
Molecular Function	GO:0031491	nucleosome binding	ISO	J:164563
Molecular Function	GO:0002039	p53 binding	ISA	J:103923
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030690	Noc1p-Noc2p complex	IBA	J:265628
Cellular Component	GO:0030691	Noc2p-Noc3p complex	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IBA	J:265628
Cellular Component	GO:0000786	nucleosome	ISA	J:103923
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISA	J:103923
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0002903	negative regulation of B cell apoptotic process	ISO	J:164563
Biological Process	GO:0035067	negative regulation of histone acetylation	IBA	J:265628
Biological Process	GO:0035067	negative regulation of histone acetylation	ISA	J:103923
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISA	J:103923
Biological Process	GO:0042273	ribosomal large subunit biogenesis	IBA	J:265628
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563