GO Annotations Graph

• Symbol: Hdac9
• Name: histone deacetylase 9
• ID: MGI:1931221

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:152666
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	TAS	J:113927
Molecular Function	GO:0004407	histone deacetylase activity	TAS	J:113927
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0031078	histone H3K14 deacetylase activity	IMP	J:175911
Molecular Function	GO:0032129	histone H3K9 deacetylase activity	IMP	J:175911
Molecular Function	GO:0034739	histone H4K16 deacetylase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:162637
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:279931
Molecular Function	GO:0005515	protein binding	IPI	J:70040
Molecular Function	GO:0005080	protein kinase C binding	ISO	J:164563
Molecular Function	GO:0033558	protein lysine deacetylase activity	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:67665
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	TAS	J:113927
Cellular Component	GO:0000118	histone deacetylase complex	TAS	J:113927
Cellular Component	GO:0035097	histone methyltransferase complex	IDA	J:152666
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	TAS	J:113927
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0042113	B cell activation	TAS	J:113927
Biological Process	GO:0030183	B cell differentiation	TAS	J:113927
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	TAS	J:113927
Biological Process	GO:0008340	determination of adult lifespan	IGI	J:174530
Biological Process	GO:0006281	DNA repair	IGI	J:174530
Biological Process	GO:0007507	heart development	IGI	J:93021
Biological Process	GO:0016575	histone deacetylation	IEA	J:72247
Biological Process	GO:0006954	inflammatory response	TAS	J:113927
Biological Process	GO:0001818	negative regulation of cytokine production	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TAS	J:113927
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:67665
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:102395
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	IMP	J:175911
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	ISO	J:164563
Biological Process	GO:0051005	negative regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:0045843	negative regulation of striated muscle tissue development	TAS	J:113927
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:107465
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:70040
Biological Process	GO:0007399	nervous system development	TAS	J:113927
Biological Process	GO:0034983	peptidyl-lysine deacetylation	ISO	J:164563
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	IGI	J:127416
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	IGI	J:127416
Biological Process	GO:1902809	regulation of skeletal muscle fiber differentiation	IGI	J:127416
Biological Process	GO:1902809	regulation of skeletal muscle fiber differentiation	IGI	J:127416