GO Annotations Graph

• Symbol: Nfkbiz
• Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
• ID: MGI:1931595

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:216064
Molecular Function	GO:0005515	protein binding	IPI	J:265840
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:159461
Molecular Function	GO:0003712	transcription coregulator activity	IDA	J:97246
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:97246
Cellular Component	GO:0005634	nucleus	IDA	J:265840
Cellular Component	GO:0005634	nucleus	IDA	J:65974
Biological Process	GO:0002250	adaptive immune response	IDA	J:121485
Biological Process	GO:0042100	B cell proliferation	IMP	J:200520
Biological Process	GO:0042100	B cell proliferation	IMP	J:217074
Biological Process	GO:1990117	B cell receptor apoptotic signaling pathway	IDA	J:200520
Biological Process	GO:0050853	B cell receptor signaling pathway	IDA	J:121485
Biological Process	GO:0016049	cell growth	IMP	J:253701
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:227182
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:266673
Biological Process	GO:0071345	cellular response to cytokine stimulus	IDA	J:287108
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:291029
Biological Process	GO:0097398	cellular response to interleukin-17	IMP	J:277730
Biological Process	GO:0097398	cellular response to interleukin-17	IDA	J:290097
Biological Process	GO:0097398	cellular response to interleukin-17	IMP	J:291029
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:235017
Biological Process	GO:0071310	cellular response to organic substance	IMP	J:290097
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IMP	J:242738
Biological Process	GO:0032602	chemokine production	IMP	J:95040
Biological Process	GO:0032602	chemokine production	IMP	J:253701
Biological Process	GO:0032602	chemokine production	IMP	J:255633
Biological Process	GO:0032602	chemokine production	IMP	J:287108
Biological Process	GO:0006325	chromatin organization	IMP	J:136566
Biological Process	GO:0006325	chromatin organization	IMP	J:217074
Biological Process	GO:0006338	chromatin remodeling	IDA	J:235017
Biological Process	GO:0006338	chromatin remodeling	IMP	J:235017
Biological Process	GO:0002544	chronic inflammatory response	IMP	J:290097
Biological Process	GO:0001816	cytokine production	IMP	J:253701
Biological Process	GO:0001816	cytokine production	IMP	J:279757
Biological Process	GO:0001816	cytokine production	IMP	J:287108
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:266673
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:291029
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:279757
Biological Process	GO:1904019	epithelial cell apoptotic process	IMP	J:194832
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:253701
Biological Process	GO:0097194	execution phase of apoptosis	IMP	J:255633
Biological Process	GO:0010467	gene expression	IMP	J:95040
Biological Process	GO:0010467	gene expression	IDA	J:97246
Biological Process	GO:0010467	gene expression	IMP	J:136566
Biological Process	GO:0010467	gene expression	IMP	J:141704
Biological Process	GO:0010467	gene expression	IMP	J:159461
Biological Process	GO:0010467	gene expression	IMP	J:200520
Biological Process	GO:0010467	gene expression	IMP	J:227182
Biological Process	GO:0010467	gene expression	IMP	J:235017
Biological Process	GO:0010467	gene expression	IDA	J:265840
Biological Process	GO:0010467	gene expression	IMP	J:266673
Biological Process	GO:0010467	gene expression	IMP	J:287108
Biological Process	GO:0010467	gene expression	IMP	J:291029
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:242738
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:217074
Biological Process	GO:0002377	immunoglobulin production	IMP	J:95040
Biological Process	GO:0002377	immunoglobulin production	IMP	J:279757
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	IMP	J:141704
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	IMP	J:253701
Biological Process	GO:0006954	inflammatory response	IMP	J:95040
Biological Process	GO:0006954	inflammatory response	IMP	J:141704
Biological Process	GO:0006954	inflammatory response	IMP	J:194832
Biological Process	GO:0006954	inflammatory response	IMP	J:227182
Biological Process	GO:0006954	inflammatory response	IMP	J:253701
Biological Process	GO:0006954	inflammatory response	IMP	J:266673
Biological Process	GO:0006954	inflammatory response	IMP	J:291029
Biological Process	GO:0006954	inflammatory response	IDA	J:65974
Biological Process	GO:0090594	inflammatory response to wounding	IDA	J:255633
Biological Process	GO:0032613	interleukin-10 production	IMP	J:235017
Biological Process	GO:0045190	isotype switching	IMP	J:217074
Biological Process	GO:0045190	isotype switching	IMP	J:279757
Biological Process	GO:0032980	keratinocyte activation	IMP	J:95040
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:227182
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:227182
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:266673
Biological Process	GO:0002285	lymphocyte activation involved in immune response	IMP	J:194832
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IMP	J:235017
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IDA	J:235017
Biological Process	GO:0002317	plasma cell differentiation	IMP	J:217074
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:2000321	positive regulation of T-helper 17 cell differentiation	IMP	J:259145
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:235017
Biological Process	GO:0010468	regulation of gene expression	IBA	J:265628
Biological Process	GO:0050776	regulation of immune response	IMP	J:242738
Biological Process	GO:0072718	response to cisplatin	IDA	J:255633
Biological Process	GO:0034097	response to cytokine	IMP	J:255633
Biological Process	GO:0051593	response to folic acid	IDA	J:255633
Biological Process	GO:0140459	response to Gram-positive bacterium	IMP	J:253701
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:255633
Biological Process	GO:0010033	response to organic substance	IDA	J:261637
Biological Process	GO:0010033	response to organic substance	IMP	J:261637
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:291029
Biological Process	GO:0043588	skin development	IMP	J:95040
Biological Process	GO:0043588	skin development	IMP	J:227182
Biological Process	GO:0043588	skin development	IMP	J:266673
Biological Process	GO:0043588	skin development	IMP	J:291029
Biological Process	GO:0098773	skin epidermis development	IMP	J:95040
Biological Process	GO:0048536	spleen development	IMP	J:279757
Biological Process	GO:0030217	T cell differentiation	IMP	J:242738
Biological Process	GO:0030217	T cell differentiation	IMP	J:279757
Biological Process	GO:0002456	T cell mediated immunity	IMP	J:279757
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:259145
Biological Process	GO:0045063	T-helper 1 cell differentiation	IMP	J:279757
Biological Process	GO:0072539	T-helper 17 cell differentiation	IMP	J:159461
Biological Process	GO:0002224	toll-like receptor signaling pathway	IMP	J:200520
Biological Process	GO:0002224	toll-like receptor signaling pathway	IDA	J:200520
Biological Process	GO:0002224	toll-like receptor signaling pathway	IMP	J:217074
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:159461
Biological Process	GO:0070897	transcription preinitiation complex assembly	IMP	J:136566
Biological Process	GO:0032609	type II interferon production	IMP	J:242738
Biological Process	GO:0032609	type II interferon production	IMP	J:279757