GO Annotations Graph

• Symbol: Dbn1
• Name: drebrin 1
• ID: MGI:1931838

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	ISO	J:155856
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0140661	cytoskeletal motor inhibitor activity	ISO	J:155856
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0005522	profilin binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:214682
Molecular Function	GO:0005515	protein binding	IPI	J:90107
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:76483
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0005884	actin filament	IBA	J:265628
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0044308	axonal spine	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	IDA	J:90107
Cellular Component	GO:0030864	cortical actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:1902737	dendritic filopodium	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0005921	gap junction	IDA	J:90107
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263418
Cellular Component	GO:0030426	growth cone	IDA	J:214682
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:90107
Cellular Component	GO:0044309	neuron spine	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:90107
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:263418
Cellular Component	GO:0099524	postsynaptic cytosol	IDA	J:263418
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263418
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263418
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:263418
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:263418
Cellular Component	GO:0030427	site of polarized growth	IBA	J:265628
Biological Process	GO:0007015	actin filament organization	IDA	J:76483
Biological Process	GO:0010643	cell communication by chemical coupling	IMP	J:90107
Biological Process	GO:0010644	cell communication by electrical coupling	IMP	J:90107
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	ISO	J:155856
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:155856
Biological Process	GO:0051220	cytoplasmic sequestering of protein	ISO	J:164563
Biological Process	GO:0048699	generation of neurons	IEP	J:169939
Biological Process	GO:0001701	in utero embryonic development	IMP	J:240631
Biological Process	GO:0032507	maintenance of protein location in cell	IMP	J:90107
Biological Process	GO:0098828	modulation of inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0032232	negative regulation of actin filament bundle assembly	ISO	J:155856
Biological Process	GO:0090327	negative regulation of locomotion involved in locomotory behavior	ISO	J:155856
Biological Process	GO:1904113	negative regulation of muscle filament sliding	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0061351	neural precursor cell proliferation	IEP	J:169939
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0045773	positive regulation of axon extension	ISO	J:155856
Biological Process	GO:0045773	positive regulation of axon extension	IBA	J:265628
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	IMP	J:224553
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	IBA	J:265628
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1902685	positive regulation of receptor localization to synapse	IMP	J:224553
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:155856
Biological Process	GO:0031915	positive regulation of synaptic plasticity	IMP	J:224553
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:155856
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IBA	J:265628
Biological Process	GO:0060134	prepulse inhibition	ISO	J:155856
Biological Process	GO:0030833	regulation of actin filament polymerization	ISO	J:155856
Biological Process	GO:0030833	regulation of actin filament polymerization	IBA	J:265628
Biological Process	GO:0051489	regulation of filopodium assembly	ISO	J:155856
Biological Process	GO:1902897	regulation of postsynaptic density protein 95 clustering	ISO	J:155856