GO Annotations Graph

• Symbol: Cacng8
• Name: calcium channel, voltage-dependent, gamma subunit 8
• ID: MGI:1932376

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005246	calcium channel regulator activity	IDA	J:262599
Molecular Function	GO:0005246	calcium channel regulator activity	IDA	J:260353
Molecular Function	GO:0016247	channel regulator activity	IBA	J:265628
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0030346	protein phosphatase 2B binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0032281	AMPA glutamate receptor complex	ISO	J:155856
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IBA	J:265628
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:117149
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:117149
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	IDA	J:262599
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	IDA	J:167716
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:231740
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:231740
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:231740
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:231740
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:117149
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:117149
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0099590	neurotransmitter receptor internalization	IBA	J:265628
Biological Process	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	IBA	J:265628
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping	IBA	J:265628
Biological Process	GO:2000311	regulation of AMPA receptor activity	ISO	J:164563
Biological Process	GO:2000311	regulation of AMPA receptor activity	ISO	J:155856
Biological Process	GO:2000311	regulation of AMPA receptor activity	IDA	J:167716
Biological Process	GO:2000311	regulation of AMPA receptor activity	IBA	J:265628
Biological Process	GO:2000311	regulation of AMPA receptor activity	IDA	J:260353
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IMP	J:117149
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IMP	J:117149
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:117149
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	IDA	J:117149
Biological Process	GO:0019226	transmission of nerve impulse	IBA	J:265628