GO Annotations Graph

• Symbol: Phip
• Name: pleckstrin homology domain interacting protein
• ID: MGI:1932404

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005158	insulin receptor binding	IEA	J:72247
Molecular Function	GO:0070577	lysine-acetylated histone binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:66427
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:125126
Cellular Component	GO:0005634	nucleus	IDA	J:125126
Biological Process	GO:0008283	cell population proliferation	IGI	J:125126
Biological Process	GO:0008283	cell population proliferation	IGI	J:125126
Biological Process	GO:0007010	cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:164354
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:66427
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:125126
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:125126
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IDA	J:125126
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:125126
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:125126
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:164354
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	IDA	J:125126
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IMP	J:125126
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IDA	J:125126
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	IDA	J:125126
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:125126
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	IGI	J:125126
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	IGI	J:125126
Biological Process	GO:0006606	protein import into nucleus	IMP	J:164354
Biological Process	GO:0022604	regulation of cell morphogenesis	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0040008	regulation of growth	IMP	J:164354
Biological Process	GO:0001932	regulation of protein phosphorylation	IDA	J:125126
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0044342	type B pancreatic cell proliferation	IGI	J:125126
Biological Process	GO:0044342	type B pancreatic cell proliferation	IGI	J:125126