GO Annotations Graph

• Symbol: Cxcl16
• Name: C-X-C motif chemokine ligand 16
• ID: MGI:1932682

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008009	chemokine activity	ISO	J:164563
Molecular Function	GO:0008009	chemokine activity	IBA	J:265628
Molecular Function	GO:0008009	chemokine activity	IDA	J:65117
Molecular Function	GO:0042379	chemokine receptor binding	IPI	J:65117
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	IBA	J:265628
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	IDA	J:66714
Molecular Function	GO:0005044	scavenger receptor activity	IBA	J:265628
Molecular Function	GO:0005044	scavenger receptor activity	IDA	J:66714
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IDA	J:65117
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:65117
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:65117
Biological Process	GO:0006935	chemotaxis	IEA	J:72247
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0006897	endocytosis	IDA	J:66714
Biological Process	GO:0048247	lymphocyte chemotaxis	IEA	J:72247
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	IBA	J:265628
Biological Process	GO:0006898	receptor-mediated endocytosis	IEA	J:72247
Biological Process	GO:0034097	response to cytokine	ISO	J:164563
Biological Process	GO:0034612	response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0034341	response to type II interferon	ISO	J:164563
Biological Process	GO:0010818	T cell chemotaxis	IDA	J:65117
Biological Process	GO:0010818	T cell chemotaxis	IBA	J:265628