GO Annotations Graph

• Symbol: Ctns
• Name: cystinosis, nephropathic
• ID: MGI:1932872

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IMP	J:79610
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IMP	J:149574
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IDA	J:79610
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IMP	J:149574
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IMP	J:149574
Molecular Function	GO:0015184	L-cystine transmembrane transporter activity	IMP	J:149574
Molecular Function	GO:0015295	solute:proton symporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IDA	J:79610
Cellular Component	GO:0005764	lysosome	ISO	J:135985
Cellular Component	GO:0005764	lysosome	ISO	J:135985
Cellular Component	GO:0042470	melanosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:135985
Biological Process	GO:0007628	adult walking behavior	IMP	J:149574
Biological Process	GO:0046034	ATP metabolic process	ISO	J:164563
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0050890	cognition	ISO	J:164563
Biological Process	GO:0006749	glutathione metabolic process	ISO	J:164563
Biological Process	GO:0007625	grooming behavior	IMP	J:149574
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	IMP	J:149574
Biological Process	GO:0015811	L-cystine transport	ISO	J:164563
Biological Process	GO:0015811	L-cystine transport	ISO	J:164563
Biological Process	GO:0015811	L-cystine transport	ISO	J:155856
Biological Process	GO:0015811	L-cystine transport	IBA	J:265628
Biological Process	GO:0015811	L-cystine transport	IMP	J:179515
Biological Process	GO:0015811	L-cystine transport	IMP	J:149574
Biological Process	GO:0015811	L-cystine transport	IMP	J:79610
Biological Process	GO:0015811	L-cystine transport	IMP	J:149574
Biological Process	GO:0015811	L-cystine transport	ISO	J:135985
Biological Process	GO:0015811	L-cystine transport	IDA	J:79610
Biological Process	GO:0015811	L-cystine transport	IMP	J:149574
Biological Process	GO:0015811	L-cystine transport	IMP	J:149574
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:179515
Biological Process	GO:0007616	long-term memory	IMP	J:149574
Biological Process	GO:0042438	melanin biosynthetic process	IEA	J:60000
Biological Process	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process	ISO	J:155856
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	ISO	J:155856
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	ISO	J:155856
Biological Process	GO:1904263	positive regulation of TORC1 signaling	IMP	J:302462
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0048021	regulation of melanin biosynthetic process	ISO	J:164563
Biological Process	GO:0008542	visual learning	IMP	J:149574