GO Annotations Graph

• Symbol: Cdk5rap3
• Name: CDK5 regulatory subunit associated protein 3
• ID: MGI:1933126

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030332	cyclin binding	ISO	J:164563
Molecular Function	GO:0097371	MDM2/MDM4 family protein binding	ISO	J:164563
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	ISO	J:164563
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:217277
Molecular Function	GO:0005515	protein binding	IPI	J:272566
Molecular Function	GO:0005515	protein binding	IPI	J:106776
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	IPI	J:217277
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	ISO	J:162095
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IMP	J:272566
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:162095
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:162095
Biological Process	GO:0030262	apoptotic nuclear changes	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0060318	definitive erythrocyte differentiation	IMP	J:272566
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	ISO	J:164563
Biological Process	GO:0001889	liver development	IMP	J:272566
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	ISO	J:164563
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:1901798	positive regulation of signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:106776
Biological Process	GO:0071569	protein ufmylation	ISO	J:164563
Biological Process	GO:0071569	protein ufmylation	IMP	J:272566
Biological Process	GO:0071569	protein ufmylation	ISO	J:195351
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Biological Process	GO:0007346	regulation of mitotic cell cycle	IBA	J:265628
Biological Process	GO:0010921	regulation of phosphatase activity	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:272566