GO Annotations Graph

• Symbol: Grin3a
• Name: glutamate receptor ionotropic, NMDA3A
• ID: MGI:1933206

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IDA	J:66481
Molecular Function	GO:0005262	calcium channel activity	IMP	J:85752
Molecular Function	GO:0008066	glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0016594	glycine binding	ISO	J:164563
Molecular Function	GO:0016594	glycine binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0042165	neurotransmitter binding	ISO	J:155856
Molecular Function	GO:0004972	NMDA glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0004972	NMDA glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0004972	NMDA glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0004972	NMDA glutamate receptor activity	IMP	J:85752
Molecular Function	GO:0004972	NMDA glutamate receptor activity	IPI	J:66481
Molecular Function	GO:0005515	protein binding	IPI	J:205503
Molecular Function	GO:0005515	protein binding	IPI	J:66481
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA	J:265628
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:265614
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:265614
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:253352
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:253352
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:265614
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:265614
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IDA	J:85752
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	ISO	J:155856
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:66481
Cellular Component	GO:0045202	synapse	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:85752
Biological Process	GO:0016358	dendrite development	IMP	J:66481
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	ISO	J:155856
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0061000	negative regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:0060134	prepulse inhibition	IMP	J:102120
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:253352
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:253352
Biological Process	GO:0045471	response to ethanol	ISO	J:164563
Biological Process	GO:0048511	rhythmic process	ISO	J:155856
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628