GO Annotations Graph

• Symbol: Trim8
• Name: tripartite motif-containing 8
• ID: MGI:1933302

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:79351
Molecular Function	GO:0005515	protein binding	IPI	J:177748
Molecular Function	GO:0005515	protein binding	IPI	J:69273
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	NAS	J:79351
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:177748
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:69273
Cellular Component	GO:0016605	PML body	ISO	J:164563
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IDA	J:205675
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IDA	J:205675
Biological Process	GO:0032897	negative regulation of viral transcription	IDA	J:205675
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	IMP	J:177748
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:177748
Biological Process	GO:0044790	suppression of viral release by host	IDA	J:205675
Biological Process	GO:0044790	suppression of viral release by host	ISO	J:164563