GO Annotations Graph

• Symbol: Ifitm2
• Name: interferon induced transmembrane protein 2
• ID: MGI:1933382

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0031901	early endosome membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:241516
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0051607	defense response to virus	IDA	J:157631
Biological Process	GO:0051607	defense response to virus	ISO	J:232757
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IDA	J:187558
Biological Process	GO:0046597	negative regulation of viral entry into host cell	ISO	J:164563
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IBA	J:265628
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	IBA	J:265628
Biological Process	GO:0032897	negative regulation of viral transcription	ISO	J:164563
Biological Process	GO:0035455	response to interferon-alpha	ISO	J:164563
Biological Process	GO:0035455	response to interferon-alpha	IBA	J:265628
Biological Process	GO:0035456	response to interferon-beta	ISO	J:164563
Biological Process	GO:0035456	response to interferon-beta	IBA	J:265628
Biological Process	GO:0034341	response to type II interferon	ISO	J:164563
Biological Process	GO:0034341	response to type II interferon	IBA	J:265628
Biological Process	GO:0009615	response to virus	ISO	J:164563
Biological Process	GO:0009615	response to virus	IDA	J:187558
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IBA	J:265628