Akr1c6 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Akr1c6
aldo-keto reductase family 1, member C6
MGI:1933427

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047020	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	ISO	J:164563
Molecular Function	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	ISO	J:164563
Molecular Function	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	ISO	J:164563
Molecular Function	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	ISO	J:164563
Molecular Function	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	IBA	J:265628
Molecular Function	GO:0004033	aldo-keto reductase (NADP) activity	ISO	J:164563
Molecular Function	GO:0047042	androsterone dehydrogenase (B-specific) activity	ISO	J:164563
Molecular Function	GO:0047023	androsterone dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0047023	androsterone dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0047023	androsterone dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0032052	bile acid binding	ISO	J:164563
Molecular Function	GO:0032052	bile acid binding	ISO	J:164563
Molecular Function	GO:0032052	bile acid binding	IBA	J:265628
Molecular Function	GO:0031406	carboxylic acid binding	ISO	J:164563
Molecular Function	GO:0031406	carboxylic acid binding	ISO	J:164563
Molecular Function	GO:0047743	chlordecone reductase activity	ISO	J:164563
Molecular Function	GO:0047787	delta4-3-oxosteroid 5beta-reductase activity	ISO	J:164563
Molecular Function	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	IDA	J:25103
Molecular Function	GO:0045550	geranylgeranyl reductase activity	ISO	J:164563
Molecular Function	GO:0045703	ketoreductase activity	ISO	J:164563
Molecular Function	GO:0047086	ketosteroid monooxygenase activity	ISO	J:164563
Molecular Function	GO:0047086	ketosteroid monooxygenase activity	ISO	J:164563
Molecular Function	GO:0047086	ketosteroid monooxygenase activity	ISO	J:164563
Molecular Function	GO:0047086	ketosteroid monooxygenase activity	IBA	J:265628
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	ISO	J:164563
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	ISO	J:164563
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	ISO	J:164563
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	ISO	J:164563
Molecular Function	GO:0018636	phenanthrene 9,10-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0018636	phenanthrene 9,10-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0018636	phenanthrene 9,10-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0001758	retinal dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0001758	retinal dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity	ISO	J:155856
Molecular Function	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Biological Process	GO:0044597	daunorubicin metabolic process	IBA	J:265628
Biological Process	GO:0044598	doxorubicin metabolic process	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	IMP	J:204486
Biological Process	GO:0042448	progesterone metabolic process	IBA	J:265628
Biological Process	GO:0006693	prostaglandin metabolic process	IBA	J:265628
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	IDA	J:25103

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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