GO Annotations Graph

• Symbol: Jam2
• Name: junction adhesion molecule 2
• ID: MGI:1933820

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:106527
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:276400
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0044291	cell-cell contact zone	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0098636	protein complex involved in cell adhesion	ISO	J:164563
Cellular Component	GO:0098636	protein complex involved in cell adhesion	IBA	J:265628
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:240335
Cellular Component	GO:0070160	tight junction	IDA	J:92665
Cellular Component	GO:0070160	tight junction	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:225263
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:164563
Biological Process	GO:0045123	cellular extravasation	IDA	J:276400
Biological Process	GO:0045123	cellular extravasation	ISO	J:164563
Biological Process	GO:0097241	hematopoietic stem cell migration to bone marrow	IMP	J:225263
Biological Process	GO:0097241	hematopoietic stem cell migration to bone marrow	ISO	J:164563
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IBA	J:265628
Biological Process	GO:0050901	leukocyte tethering or rolling	ISO	J:164563
Biological Process	GO:0050901	leukocyte tethering or rolling	IDA	J:276411
Biological Process	GO:0071593	lymphocyte aggregation	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	IGI	J:106527
Biological Process	GO:0007162	negative regulation of cell adhesion	IGI	J:106527
Biological Process	GO:0007162	negative regulation of cell adhesion	IGI	J:106527
Biological Process	GO:0031642	negative regulation of myelination	IMP	J:240335
Biological Process	GO:2000403	positive regulation of lymphocyte migration	ISO	J:164563
Biological Process	GO:2000403	positive regulation of lymphocyte migration	IMP	J:276400
Biological Process	GO:0007286	spermatid development	IDA	J:92665