GO Annotations Graph

• Symbol: Pip4k2b
• Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
• ID: MGI:1934234

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	ISO	J:164563
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	ISO	J:38804
Molecular Function	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016307	phosphatidylinositol phosphate kinase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:38804
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005776	autophagosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:1902635	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0061909	autophagosome-lysosome fusion	IMP	J:262397
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0090217	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	ISO	J:164563
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IDA	J:38804
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:2000786	positive regulation of autophagosome assembly	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	IMP	J:262397
Biological Process	GO:0010506	regulation of autophagy	ISO	J:164563