GO Annotations Graph

• Symbol: Rnf31
• Name: ring finger protein 31
• ID: MGI:1934704

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:1990450	linear polyubiquitin binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:200492
Molecular Function	GO:0005515	protein binding	IPI	J:170302
Molecular Function	GO:0005515	protein binding	IPI	J:201885
Molecular Function	GO:0005515	protein binding	IPI	J:170809
Molecular Function	GO:0005515	protein binding	IPI	J:213524
Molecular Function	GO:0005515	protein binding	IPI	J:87379
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0035631	CD40 receptor complex	IDA	J:161997
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	IDA	J:161997
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	IDA	J:87379
Cellular Component	GO:0005829	cytosol	IDA	J:87379
Cellular Component	GO:0071797	LUBAC complex	ISO	J:164563
Biological Process	GO:0023035	CD40 signaling pathway	IMP	J:161997
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0060546	negative regulation of necroptotic process	IGI	J:202809
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:161997
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1904417	positive regulation of xenophagy	ISO	J:164563
Biological Process	GO:0097039	protein linear polyubiquitination	ISO	J:164563
Biological Process	GO:0097039	protein linear polyubiquitination	IBA	J:265628
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IMP	J:161997
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563