GO Annotations Graph

• Symbol: Nucks1
• Name: nuclear casein kinase and cyclin-dependent kinase substrate 1
• ID: MGI:1934811

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:226101
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:233594
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:233594
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:68910
Biological Process	GO:0071481	cellular response to X-ray	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IMP	J:211777
Biological Process	GO:0006325	chromatin organization	IMP	J:226101
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0042593	glucose homeostasis	IMP	J:211777
Biological Process	GO:0036297	interstrand cross-link repair	ISO	J:164563
Biological Process	GO:0036297	interstrand cross-link repair	IBA	J:265628
Biological Process	GO:0001678	intracellular glucose homeostasis	IMP	J:226101
Biological Process	GO:1990968	modulation by host of RNA binding by virus	ISO	J:164563
Biological Process	GO:0044827	modulation by host of viral genome replication	ISO	J:164563
Biological Process	GO:1990969	modulation by host of viral RNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0044829	positive regulation by host of viral genome replication	ISO	J:164563
Biological Process	GO:0043923	positive regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	IMP	J:211777
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:211777
Biological Process	GO:0006275	regulation of DNA replication	ISO	J:164563
Biological Process	GO:0060382	regulation of DNA strand elongation	ISO	J:164563
Biological Process	GO:0046626	regulation of insulin receptor signaling pathway	IMP	J:226101
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IC	J:226101
Biological Process	GO:0031297	replication fork processing	ISO	J:164563