GO Annotations Graph

• Symbol: Ube2n
• Name: ubiquitin-conjugating enzyme E2N
• ID: MGI:1934835

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:259118
Molecular Function	GO:0005515	protein binding	IPI	J:205449
Molecular Function	GO:0005515	protein binding	IPI	J:75985
Molecular Function	GO:0005515	protein binding	IPI	J:75985
Molecular Function	GO:0005515	protein binding	IPI	J:205449
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IDA	J:240887
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IDA	J:259118
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IBA	J:265628
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IDA	J:199676
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	IDA	J:75985
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:155856
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:92954
Cellular Component	GO:0032991	protein-containing complex	ISO	J:199676
Cellular Component	GO:0031372	UBC13-MMS2 complex	ISO	J:164563
Cellular Component	GO:0035370	UBC13-UEV1A complex	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0000729	DNA double-strand break processing	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0016574	histone ubiquitination	ISO	J:164563
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:2000781	positive regulation of double-strand break repair	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:1902533	positive regulation of intracellular signal transduction	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISS	J:122697
Biological Process	GO:1902523	positive regulation of protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0051443	positive regulation of ubiquitin-protein transferase activity	ISO	J:164563
Biological Process	GO:0006301	postreplication repair	ISO	J:164563
Biological Process	GO:0006301	postreplication repair	IBA	J:265628
Biological Process	GO:0070534	protein K63-linked ubiquitination	IDA	J:259118
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0070534	protein K63-linked ubiquitination	IDA	J:240887
Biological Process	GO:0070534	protein K63-linked ubiquitination	IBA	J:265628
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0033182	regulation of histone ubiquitination	ISO	J:164563
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050852	T cell receptor signaling pathway	ISS	J:122695
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IDA	J:75985