Vangl2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vangl2
VANGL planar cell polarity 2
MGI:2135272

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:169104
Molecular Function	GO:0005515	protein binding	IPI	J:197374
Molecular Function	GO:0005515	protein binding	IPI	J:187547
Molecular Function	GO:0005515	protein binding	IPI	J:168261
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:108647
Molecular Function	GO:0005515	protein binding	IPI	J:145627
Molecular Function	GO:0005515	protein binding	IPI	J:217667
Molecular Function	GO:0005515	protein binding	IPI	J:163736
Molecular Function	GO:0005515	protein binding	IPI	J:152701
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:205269
Molecular Function	GO:0005515	protein binding	IPI	J:217667
Cellular Component	GO:0090651	apical cytoplasm	IDA	J:222454
Cellular Component	GO:0090651	apical cytoplasm	IDA	J:222454
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108647
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108647
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:168261
Cellular Component	GO:0071944	cell periphery	IDA	J:158680
Cellular Component	GO:0060187	cell pole	IDA	J:149821
Cellular Component	GO:0005911	cell-cell junction	IDA	J:168261
Cellular Component	GO:0005911	cell-cell junction	IDA	J:217667
Cellular Component	GO:0005911	cell-cell junction	IDA	J:122585
Cellular Component	GO:0005911	cell-cell junction	IDA	J:163736
Cellular Component	GO:0030134	COPII-coated ER to Golgi transport vesicle	IDA	J:158452
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:122585
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:161641
Cellular Component	GO:0016020	membrane	ISS	J:95171
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551566
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551572
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4608838
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4608842
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:205269
Cellular Component	GO:0005886	plasma membrane	IDA	J:116150
Cellular Component	GO:0005886	plasma membrane	IDA	J:158680
Cellular Component	GO:0001725	stress fiber	IDA	J:205269
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:145627
Biological Process	GO:0045176	apical protein localization	IMP	J:105752
Biological Process	GO:0045176	apical protein localization	IMP	J:108647
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	TAS	J:169941
Biological Process	GO:0060947	cardiac vascular smooth muscle cell differentiation	TAS	J:169941
Biological Process	GO:0035787	cell migration involved in kidney development	IMP	J:168261
Biological Process	GO:0090102	cochlea development	IGI	J:131308
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:165556
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:140886
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:122585
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:100861
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:142392
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:162624
Biological Process	GO:0060028	convergent extension involved in axis elongation	IMP	J:119920
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IMP	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IGI	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IMP	J:119920
Biological Process	GO:0060029	convergent extension involved in organogenesis	IGI	J:122585
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0036514	dopaminergic neuron axon guidance	IMP	J:166974
Biological Process	GO:0003347	epicardial cell to mesenchymal cell transition	TAS	J:169941
Biological Process	GO:0048105	establishment of body hair planar orientation	IMP	J:145627
Biological Process	GO:0090162	establishment of epithelial cell polarity	TAS	J:169941
Biological Process	GO:0001736	establishment of planar polarity	IMP	J:83127
Biological Process	GO:0001736	establishment of planar polarity	IMP	J:106431
Biological Process	GO:0001736	establishment of planar polarity	IBA	J:265628
Biological Process	GO:0001736	establishment of planar polarity	IGI	J:162624
Biological Process	GO:0090177	establishment of planar polarity involved in neural tube closure	IMP	J:140886
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IMP	J:119451
Biological Process	GO:0032835	glomerulus development	IMP	J:166958
Biological Process	GO:0001942	hair follicle development	IMP	J:145627
Biological Process	GO:0001947	heart looping	IMP	J:74156
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IMP	J:198639
Biological Process	GO:0060119	inner ear receptor cell development	IGI	J:165556
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IGI	J:198639
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IMP	J:140886
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IGI	J:131308
Biological Process	GO:0060993	kidney morphogenesis	IMP	J:166958
Biological Process	GO:0060490	lateral sprouting involved in lung morphogenesis	IMP	J:159690
Biological Process	GO:0003149	membranous septum morphogenesis	IGI	J:165556
Biological Process	GO:0003149	membranous septum morphogenesis	IGI	J:165556
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0003150	muscular septum morphogenesis	IGI	J:165556
Biological Process	GO:0003150	muscular septum morphogenesis	IGI	J:165556
Biological Process	GO:0001843	neural tube closure	IGI	J:119920
Biological Process	GO:0001843	neural tube closure	IGI	J:91298
Biological Process	GO:0001843	neural tube closure	IMP	J:81365
Biological Process	GO:0001843	neural tube closure	IGI	J:119920
Biological Process	GO:0001843	neural tube closure	IGI	J:167834
Biological Process	GO:0001843	neural tube closure	IGI	J:85744
Biological Process	GO:0001843	neural tube closure	IGI	J:122585
Biological Process	GO:0001843	neural tube closure	IGI	J:198639
Biological Process	GO:0001843	neural tube closure	IMP	J:72911
Biological Process	GO:0001843	neural tube closure	IGI	J:158452
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IMP	J:149821
Biological Process	GO:1905515	non-motile cilium assembly	IGI	J:102697
Biological Process	GO:1905515	non-motile cilium assembly	IGI	J:102697
Biological Process	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	IMP	J:159690
Biological Process	GO:0003148	outflow tract septum morphogenesis	TAS	J:169941
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:1904938	planar cell polarity pathway involved in axon guidance	IMP	J:166974
Biological Process	GO:0061346	planar cell polarity pathway involved in heart morphogenesis	IMP	J:205269
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:165556
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:163834
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IMP	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:142392
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:165556
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:162624
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:163834
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	IMP	J:159690
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:174196
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IMP	J:159690
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IMP	J:205269
Biological Process	GO:0007266	Rho protein signal transduction	IMP	J:159690
Biological Process	GO:0036515	serotonergic neuron axon guidance	IMP	J:166974
Biological Process	GO:0048103	somatic stem cell division	IMP	J:149821
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:149821
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IBA	J:265628
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IGI	J:152701
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:100861
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IGI	J:122585
Biological Process	GO:0042060	wound healing	IGI	J:198639
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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