GO Annotations Graph

• Symbol: Hadha
• Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
• ID: MGI:2135593

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	ISO	J:155856
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	ISO	J:155856
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	IBA	J:265628
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	TAS	J:69846
Molecular Function	GO:0000062	fatty-acyl-CoA binding	ISO	J:155856
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	IDA	J:101983
Molecular Function	GO:0016508	long-chain-enoyl-CoA hydratase activity	ISO	J:155856
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0051287	NAD binding	ISO	J:155856
Molecular Function	GO:0070403	NAD+ binding	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:271253
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	ISO	J:164563
Cellular Component	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	ISO	J:155856
Cellular Component	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	IBA	J:265628
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	TAS	J:69846
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:0035965	cardiolipin acyl-chain remodeling	ISO	J:164563
Biological Process	GO:0006635	fatty acid beta-oxidation	ISO	J:164563
Biological Process	GO:0006635	fatty acid beta-oxidation	ISO	J:155856
Biological Process	GO:0006635	fatty acid beta-oxidation	IBA	J:265628
Biological Process	GO:0006635	fatty acid beta-oxidation	IMP	J:69846
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0032868	response to insulin	IMP	J:101304
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856