GO Annotations Graph

• Symbol: Pard3
• Name: par-3 family cell polarity regulator
• ID: MGI:2135608

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0035091	phosphatidylinositol binding	IBA	J:265628
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:155856
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ISO	J:155856
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:113906
Molecular Function	GO:0005515	protein binding	IPI	J:194840
Molecular Function	GO:0005515	protein binding	IPI	J:195218
Molecular Function	GO:0005515	protein binding	IPI	J:177468
Molecular Function	GO:0005515	protein binding	IPI	J:128950
Molecular Function	GO:0005515	protein binding	IPI	J:128950
Molecular Function	GO:0005515	protein binding	IPI	J:152567
Molecular Function	GO:0005515	protein binding	IPI	J:156525
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:156525
Cellular Component	GO:0005912	adherens junction	IDA	J:78857
Cellular Component	GO:0005912	adherens junction	IDA	J:82002
Cellular Component	GO:0043296	apical junction complex	IBA	J:265628
Cellular Component	GO:0043296	apical junction complex	IDA	J:213985
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0045177	apical part of cell	IDA	J:171504
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:113906
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:73065
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IDA	J:152567
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:97223
Cellular Component	GO:0005737	cytoplasm	IDA	J:98299
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0033269	internode region of axon	IDA	J:177468
Cellular Component	GO:0043219	lateral loop	IDA	J:159103
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0120157	PAR polarity complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	IDA	J:159103
Cellular Component	GO:0005819	spindle	IDA	J:98299
Biological Process	GO:0003383	apical constriction	IGI	J:174450
Biological Process	GO:0003383	apical constriction	IGI	J:174450
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0098609	cell-cell adhesion	IC	J:82002
Biological Process	GO:0051642	centrosome localization	IMP	J:152567
Biological Process	GO:0030010	establishment of cell polarity	IBA	J:265628
Biological Process	GO:0051660	establishment of centrosome localization	IBA	J:265628
Biological Process	GO:0090162	establishment of epithelial cell polarity	ISO	J:155856
Biological Process	GO:0007163	establishment or maintenance of cell polarity	TAS	J:113906
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	ISO	J:164563
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IBA	J:265628
Biological Process	GO:0000226	microtubule cytoskeleton organization	IBA	J:265628
Biological Process	GO:0000226	microtubule cytoskeleton organization	IMP	J:152567
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:177468
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	IMP	J:177468
Biological Process	GO:0031643	positive regulation of myelination	IMP	J:177468
Biological Process	GO:0002092	positive regulation of receptor internalization	IMP	J:195218
Biological Process	GO:0008104	protein localization	IBA	J:265628
Biological Process	GO:0006612	protein targeting to membrane	ISO	J:155856
Biological Process	GO:0032970	regulation of actin filament-based process	IGI	J:174450
Biological Process	GO:0032970	regulation of actin filament-based process	IGI	J:174450
Biological Process	GO:0060341	regulation of cellular localization	ISO	J:155856
Biological Process	GO:0044319	wound healing, spreading of cells	IMP	J:152567