GO Annotations Graph

• Symbol: Lin7a
• Name: lin-7 homolog A, crumbs cell polarity complex component
• ID: MGI:2135609

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097016	L27 domain binding	ISO	J:164563
Molecular Function	GO:0097016	L27 domain binding	IBA	J:265628
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:159058
Molecular Function	GO:0005515	protein binding	IPI	J:169741
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Molecular Function	GO:0005515	protein binding	IPI	J:144247
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:80555
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:169741
Cellular Component	GO:0097025	MPP7-DLG1-LIN7 complex	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0030658	transport vesicle membrane	TAS	Reactome:R-MMU-9610428
Cellular Component	GO:0030658	transport vesicle membrane	TAS	Reactome:R-MMU-9610641
Biological Process	GO:0006887	exocytosis	IEA	J:60000
Biological Process	GO:0048839	inner ear development	IDA	J:174607
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	IBA	J:265628
Biological Process	GO:0007269	neurotransmitter secretion	IBA	J:265628
Biological Process	GO:0007269	neurotransmitter secretion	IGI	J:102649
Biological Process	GO:0007269	neurotransmitter secretion	IGI	J:102649
Biological Process	GO:1903361	protein localization to basolateral plasma membrane	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0048489	synaptic vesicle transport	IMP	J:86623