GO Annotations Graph

• Symbol: Lmod2
• Name: leiomodin 2 (cardiac)
• ID: MGI:2135672

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0003785	actin monomer binding	ISO	J:164563
Molecular Function	GO:0005523	tropomyosin binding	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0097512	cardiac myofibril	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0031430	M band	ISO	J:164563
Cellular Component	GO:0031430	M band	ISO	J:155856
Cellular Component	GO:0030016	myofibril	ISO	J:164563
Cellular Component	GO:0030016	myofibril	IBA	J:265628
Cellular Component	GO:0030017	sarcomere	ISO	J:164563
Cellular Component	GO:0030017	sarcomere	ISO	J:155856
Cellular Component	GO:0005865	striated muscle thin filament	IBA	J:265628
Biological Process	GO:0030041	actin filament polymerization	IMP	J:227272
Biological Process	GO:0045010	actin nucleation	ISO	J:164563
Biological Process	GO:0006936	muscle contraction	IBA	J:265628
Biological Process	GO:0030239	myofibril assembly	IBA	J:265628
Biological Process	GO:0051694	pointed-end actin filament capping	IEA	J:72247
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	ISO	J:155856
Biological Process	GO:0045214	sarcomere organization	IMP	J:233669