GO Annotations Graph

• Symbol: Crb1
• Name: crumbs family member 1, photoreceptor morphogenesis associated
• ID: MGI:2136343

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:92068
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:92068
Cellular Component	GO:0043296	apical junction complex	IDA	J:92068
Cellular Component	GO:0045177	apical part of cell	IDA	J:220858
Cellular Component	GO:0045177	apical part of cell	IDA	J:220858
Cellular Component	GO:0045177	apical part of cell	IDA	J:220858
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:117415
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0097386	glial cell projection	IDA	J:306611
Cellular Component	GO:0097386	glial cell projection	IDA	J:114927
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005902	microvillus	IDA	J:114927
Cellular Component	GO:0001917	photoreceptor inner segment	ISO	J:155856
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:92068
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:114927
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IBA	J:265628
Cellular Component	GO:0035003	subapical complex	IDA	J:117415
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:216513
Biological Process	GO:0071482	cellular response to light stimulus	IMP	J:117415
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	IMP	J:182353
Biological Process	GO:0061159	establishment of bipolar cell polarity involved in cell morphogenesis	IMP	J:92068
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IBA	J:265628
Biological Process	GO:0042462	eye photoreceptor cell development	IMP	J:85459
Biological Process	GO:0042462	eye photoreceptor cell development	IMP	J:166679
Biological Process	GO:0010467	gene expression	IMP	J:117415
Biological Process	GO:0010001	glial cell differentiation	IMP	J:216513
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA	J:265628
Biological Process	GO:0061024	membrane organization	IMP	J:85459
Biological Process	GO:0061024	membrane organization	IMP	J:85459
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:117415
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:216513
Biological Process	GO:0035845	photoreceptor cell outer segment organization	IMP	J:85459
Biological Process	GO:0007009	plasma membrane organization	IMP	J:92068
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	IMP	J:85459
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	IMP	J:92068
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	IMP	J:114927
Biological Process	GO:0008104	protein localization	IMP	J:114927
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:182353
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:216513
Biological Process	GO:0010842	retina layer formation	IMP	J:117415
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:85459
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:117415
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:216513
Biological Process	GO:0007601	visual perception	IMP	J:85459
Biological Process	GO:0007601	visual perception	IMP	J:92068