GO Annotations Graph

• Symbol: Sarm1
• Name: sterile alpha and HEAT/Armadillo motif containing 1
• ID: MGI:2136419

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0050135	NAD(P)+ nucleosidase activity	IEA	J:72245
Molecular Function	GO:0003953	NAD+ nucleosidase activity	ISO	J:164563
Molecular Function	GO:0003953	NAD+ nucleosidase activity	IDA	J:256058
Molecular Function	GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:176666
Molecular Function	GO:0005515	protein binding	IPI	J:172355
Molecular Function	GO:0005515	protein binding	IPI	J:126083
Molecular Function	GO:0035591	signaling adaptor activity	IEA	J:72247
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:126083
Cellular Component	GO:0030425	dendrite	IMP	J:172355
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005874	microtubule	IDA	J:126083
Cellular Component	GO:0015630	microtubule cytoskeleton	IDA	J:126083
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:126083
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:126083
Cellular Component	GO:0045202	synapse	IDA	J:172355
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0019677	NAD catabolic process	ISO	J:164563
Biological Process	GO:0019677	NAD catabolic process	IDA	J:256058
Biological Process	GO:0019677	NAD catabolic process	IMP	J:269726
Biological Process	GO:0019677	NAD catabolic process	IMP	J:302470
Biological Process	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:1901216	positive regulation of neuron death	IMP	J:269726
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:164563
Biological Process	GO:1901216	positive regulation of neuron death	IMP	J:302470
Biological Process	GO:0048814	regulation of dendrite morphogenesis	IMP	J:172355
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:126083
Biological Process	GO:1901214	regulation of neuron death	IMP	J:126083
Biological Process	GO:1901214	regulation of neuron death	IBA	J:265628
Biological Process	GO:0048678	response to axon injury	ISO	J:164563
Biological Process	GO:0009749	response to glucose	IMP	J:126083
Biological Process	GO:0007165	signal transduction	IEA	J:72247