GO Annotations Graph

• Symbol: Rtn4r
• Name: reticulon 4 receptor
• ID: MGI:2136886

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035374	chondroitin sulfate binding	IDA	J:191258
Molecular Function	GO:1905573	ganglioside GM1 binding	ISO	J:164563
Molecular Function	GO:1905576	ganglioside GT1b binding	ISO	J:164563
Molecular Function	GO:0008201	heparin binding	IDA	J:191258
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0038131	neuregulin receptor activity	IDA	J:224729
Molecular Function	GO:0005515	protein binding	IPI	J:174418
Molecular Function	GO:0005515	protein binding	IPI	J:68902
Molecular Function	GO:0005515	protein binding	IPI	J:84277
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0048495	Roundabout binding	IBA	J:265628
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:155856
Cellular Component	GO:0044295	axonal growth cone	IDA	J:224729
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:182292
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0043198	dendritic shaft	IDA	J:182292
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	IDA	J:174418
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:224729
Cellular Component	GO:0043025	neuronal cell body	IDA	J:224729
Cellular Component	GO:0005886	plasma membrane	IDA	J:224729
Cellular Component	GO:0005886	plasma membrane	IDA	J:68902
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007409	axonogenesis	IDA	J:68902
Biological Process	GO:0007166	cell surface receptor signaling pathway	ISO	J:155856
Biological Process	GO:0022038	corpus callosum development	IMP	J:238817
Biological Process	GO:0050919	negative chemotaxis	IBA	J:265628
Biological Process	GO:0030517	negative regulation of axon extension	IDA	J:224729
Biological Process	GO:0048681	negative regulation of axon regeneration	IMP	J:191258
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0010977	negative regulation of neuron projection development	IMP	J:191258
Biological Process	GO:0010977	negative regulation of neuron projection development	IMP	J:94754
Biological Process	GO:0023041	neuronal signal transduction	IDA	J:224729
Biological Process	GO:0043547	positive regulation of GTPase activity	IDA	J:224729
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	ISO	J:164563