GO Annotations Graph

• Symbol: P2rx5
• Name: purinergic receptor P2X, ligand-gated ion channel, 5
• ID: MGI:2137026

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	ISO	J:155856
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	IBA	J:265628
Molecular Function	GO:0004931	extracellularly ATP-gated monoatomic cation channel activity	IDA	J:70144
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IC	J:70144
Biological Process	GO:0007166	cell surface receptor signaling pathway	TAS	J:70144
Biological Process	GO:0060079	excitatory postsynaptic potential	IDA	J:70144
Biological Process	GO:0098655	monoatomic cation transmembrane transport	IDA	J:70144
Biological Process	GO:0098655	monoatomic cation transmembrane transport	ISO	J:155856
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0043416	regulation of skeletal muscle tissue regeneration	ISO	J:155856
Biological Process	GO:0033198	response to ATP	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	ISO	J:155856
Biological Process	GO:0009268	response to pH	ISO	J:155856
Biological Process	GO:0010043	response to zinc ion	ISO	J:155856