GO Annotations Graph

• Symbol: Eefsec
• Name: eukaryotic elongation factor, selenocysteine-tRNA-specific
• ID: MGI:2137092

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	IDA	J:63958
Molecular Function	GO:0005525	GTP binding	IDA	J:64485
Molecular Function	GO:0003924	GTPase activity	IDA	J:192960
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:192960
Molecular Function	GO:0043021	ribonucleoprotein complex binding	IDA	J:192960
Molecular Function	GO:0035368	selenocysteine insertion sequence binding	IDA	J:192960
Molecular Function	GO:0003746	translation elongation factor activity	IBA	J:265628
Molecular Function	GO:0003746	translation elongation factor activity	IDA	J:192960
Molecular Function	GO:0000049	tRNA binding	IDA	J:192960
Molecular Function	GO:0000049	tRNA binding	IDA	J:63958
Molecular Function	GO:0000049	tRNA binding	IDA	J:106921
Molecular Function	GO:0000049	tRNA binding	IDA	J:64485
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2408515
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:192960
Biological Process	GO:0001514	selenocysteine incorporation	IBA	J:265628
Biological Process	GO:0001514	selenocysteine incorporation	IMP	J:75218
Biological Process	GO:0001514	selenocysteine incorporation	IDA	J:63958
Biological Process	GO:0001514	selenocysteine incorporation	IDA	J:64485
Biological Process	GO:0001514	selenocysteine incorporation	IMP	J:64667
Biological Process	GO:0001514	selenocysteine incorporation	IMP	J:192960
Biological Process	GO:0006412	translation	IEA	J:60000