GO Annotations Graph

• Symbol: Lbr
• Name: lamin B receptor
• ID: MGI:2138281

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070087	chromo shadow domain binding	ISO	J:164563
Molecular Function	GO:0050613	delta14-sterol reductase activity	ISO	J:164563
Molecular Function	GO:0050613	delta14-sterol reductase activity	IMP	J:143116
Molecular Function	GO:0050613	delta14-sterol reductase activity	IMP	J:180894
Molecular Function	GO:0050613	delta14-sterol reductase activity	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0070402	NADPH binding	ISO	J:164563
Molecular Function	GO:0008139	nuclear localization sequence binding	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:277871
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:98702
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	IDA	J:160544
Cellular Component	GO:0005637	nuclear inner membrane	ISO	J:164563
Cellular Component	GO:0005637	nuclear inner membrane	IBA	J:265628
Cellular Component	GO:0005637	nuclear inner membrane	TAS	J:74817
Cellular Component	GO:0005652	nuclear lamina	TAS	J:74817
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	IDA	J:143116
Cellular Component	GO:0005643	nuclear pore	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006695	cholesterol biosynthetic process	IDA	J:143116
Biological Process	GO:0006695	cholesterol biosynthetic process	IMP	J:180894
Biological Process	GO:0006695	cholesterol biosynthetic process	ISO	J:164563
Biological Process	GO:0006695	cholesterol biosynthetic process	IBA	J:265628
Biological Process	GO:0008203	cholesterol metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0030223	neutrophil differentiation	IMP	J:180894
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000
Biological Process	GO:0016126	sterol biosynthetic process	IEA	J:60000
Biological Process	GO:0016126	sterol biosynthetic process	IEA	J:72247