GO Annotations Graph

• Symbol: Slc4a11
• Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
• ID: MGI:2138987

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046715	active borate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0046983	protein dimerization activity	ISO	J:164563
Molecular Function	GO:0015252	proton channel activity	ISO	J:164563
Molecular Function	GO:0015078	proton transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005272	sodium channel activity	ISO	J:164563
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	IEA	J:72247
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005372	water transmembrane transporter activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:202267
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0012506	vesicle membrane	ISO	J:155856
Biological Process	GO:0015701	bicarbonate transport	ISO	J:164563
Biological Process	GO:0046713	borate transport	ISO	J:164563
Biological Process	GO:0071476	cellular hypotonic response	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0042044	fluid transport	IMP	J:162968
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	ISO	J:164563
Biological Process	GO:0006820	monoatomic anion transport	IEA	J:72247
Biological Process	GO:0050801	monoatomic ion homeostasis	IMP	J:162968
Biological Process	GO:0050801	monoatomic ion homeostasis	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:2000739	regulation of mesenchymal stem cell differentiation	IMP	J:304590
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628