GO Annotations Graph

• Symbol: Prom2
• Name: prominin 2
• ID: MGI:2138997

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015485	cholesterol binding	ISS	J:77557
Molecular Function	GO:0015485	cholesterol binding	ISO	J:155856
Molecular Function	GO:0015485	cholesterol binding	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:168820
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005929	cilium	ISS	J:77557
Cellular Component	GO:0005929	cilium	ISO	J:155856
Cellular Component	GO:0005929	cilium	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISS	J:77557
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	ISS	J:77557
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0044393	microspike	ISO	J:155856
Cellular Component	GO:0044393	microspike	ISS	J:77557
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISS	J:77557
Cellular Component	GO:0005902	microvillus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISS	J:77557
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:77557
Cellular Component	GO:0071914	prominosome	ISO	J:155856
Cellular Component	GO:0071914	prominosome	IDA	J:168820
Cellular Component	GO:0071914	prominosome	IBA	J:265628
Biological Process	GO:2001287	negative regulation of caveolin-mediated endocytosis	ISO	J:164563
Biological Process	GO:0048550	negative regulation of pinocytosis	ISO	J:164563
Biological Process	GO:0031346	positive regulation of cell projection organization	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563