GO Annotations Graph

• Symbol: Prmt6
• Name: protein arginine N-methyltransferase 6
• ID: MGI:2139971

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:199753
Molecular Function	GO:0008469	histone arginine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0070612	histone H2AR3 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0070611	histone H3R2 methyltransferase activity	IMP	J:199753
Molecular Function	GO:0044020	histone H4R3 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042054	histone methyltransferase activity	ISO	J:164563
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:224604
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	IDA	J:224604
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	IDA	J:138740
Molecular Function	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	ISO	J:164563
Molecular Function	GO:0035241	protein-arginine omega-N monomethyltransferase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	IMP	J:199753
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:199753
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	IDA	J:224604
Biological Process	GO:0018216	peptidyl-arginine methylation	IEA	J:72247
Biological Process	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	ISO	J:164563
Biological Process	GO:0036211	protein modification process	ISO	J:164563
Biological Process	GO:0010821	regulation of mitochondrion organization	ISO	J:164563
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	IMP	J:199753