GO Annotations Graph

• Symbol: Adprs
• Name: ADP-ribosylserine hydrolase
• ID: MGI:2140364

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140292	ADP-ribosylserine hydrolase activity	IMP	J:257656
Molecular Function	GO:0140292	ADP-ribosylserine hydrolase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0061463	O-acetyl-ADP-ribose deacetylase activity	ISO	J:164563
Molecular Function	GO:0004649	poly(ADP-ribose) glycohydrolase activity	IDA	J:202975
Molecular Function	GO:0004649	poly(ADP-ribose) glycohydrolase activity	ISO	J:164563
Molecular Function	GO:0004649	poly(ADP-ribose) glycohydrolase activity	IDA	J:291285
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:202975
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:202975
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:202975
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Biological Process	GO:0071451	cellular response to superoxide	ISO	J:164563
Biological Process	GO:0071451	cellular response to superoxide	IMP	J:202975
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0060546	negative regulation of necroptotic process	IDA	J:291285
Biological Process	GO:0140290	peptidyl-serine ADP-deribosylation	IDA	J:257656
Biological Process	GO:0140290	peptidyl-serine ADP-deribosylation	ISO	J:164563