GO Annotations Graph

• Symbol: Slc15a4
• Name: solute carrier family 15, member 4
• ID: MGI:2140796

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	IMP	J:264062
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	IDA	J:270965
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015333	peptide:proton symporter activity	IMP	J:264062
Molecular Function	GO:0015333	peptide:proton symporter activity	ISO	J:164563
Molecular Function	GO:0015647	peptidoglycan transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0031901	early endosome membrane	IDA	J:292537
Cellular Component	GO:0036020	endolysosome membrane	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	IDA	J:210445
Cellular Component	GO:0010008	endosome membrane	IDA	J:264062
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:210445
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:270965
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:258080
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IBA	J:265628
Biological Process	GO:0140206	dipeptide import across plasma membrane	ISO	J:164563
Biological Process	GO:0015817	histidine transport	ISO	J:155856
Biological Process	GO:0015817	histidine transport	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0089708	L-histidine transmembrane export from vacuole	IMP	J:241087
Biological Process	GO:0033023	mast cell homeostasis	IMP	J:258080
Biological Process	GO:0006857	oligopeptide transport	IEA	J:72247
Biological Process	GO:0015833	peptide transport	IEA	J:60000
Biological Process	GO:0015835	peptidoglycan transport	IMP	J:264062
Biological Process	GO:0015835	peptidoglycan transport	ISO	J:164563
Biological Process	GO:0015835	peptidoglycan transport	IDA	J:210445
Biological Process	GO:0045089	positive regulation of innate immune response	ISO	J:164563
Biological Process	GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	IMP	J:270965
Biological Process	GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	IMP	J:292537
Biological Process	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	IDA	J:210445
Biological Process	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	IMP	J:278429
Biological Process	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	IMP	J:166600
Biological Process	GO:0034157	positive regulation of toll-like receptor 7 signaling pathway	ISO	J:164563
Biological Process	GO:0034161	positive regulation of toll-like receptor 8 signaling pathway	ISO	J:164563
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	IMP	J:278429
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	ISO	J:164563
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	IMP	J:166600
Biological Process	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway	IMP	J:270965
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0048302	regulation of isotype switching to IgG isotypes	IMP	J:223449
Biological Process	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	IMP	J:264062
Biological Process	GO:0055085	transmembrane transport	IBA	J:265628