GO Annotations Graph

• Symbol: Acacb
• Name: acetyl-Coenzyme A carboxylase beta
• ID: MGI:2140940

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003989	acetyl-CoA carboxylase activity	ISO	J:164563
Molecular Function	GO:0003989	acetyl-CoA carboxylase activity	IBA	J:265628
Molecular Function	GO:0003989	acetyl-CoA carboxylase activity	IMP	J:118861
Molecular Function	GO:0003989	acetyl-CoA carboxylase activity	IDA	J:118861
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0009374	biotin binding	ISO	J:155856
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0016874	ligase activity	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IDA	J:212818
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006084	acetyl-CoA metabolic process	ISO	J:164563
Biological Process	GO:0097009	energy homeostasis	IMP	J:109697
Biological Process	GO:0006633	fatty acid biosynthetic process	IBA	J:265628
Biological Process	GO:0006633	fatty acid biosynthetic process	IMP	J:118861
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:2001295	malonyl-CoA biosynthetic process	IMP	J:138207
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0043086	negative regulation of catalytic activity	IDA	J:109697
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	IMP	J:96465
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	IMP	J:109697
Biological Process	GO:0046322	negative regulation of fatty acid oxidation	IMP	J:138207
Biological Process	GO:0046322	negative regulation of fatty acid oxidation	IMP	J:68427
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:109697
Biological Process	GO:0050995	negative regulation of lipid catabolic process	IMP	J:96465
Biological Process	GO:0060421	positive regulation of heart growth	IMP	J:138207
Biological Process	GO:0010884	positive regulation of lipid storage	IMP	J:68427
Biological Process	GO:0051289	protein homotetramerization	ISO	J:164563
Biological Process	GO:0010906	regulation of glucose metabolic process	IMP	J:96465
Biological Process	GO:0031667	response to nutrient levels	IMP	J:109697
Biological Process	GO:0031667	response to nutrient levels	IMP	J:96465
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856