GO Annotations Graph

• Symbol: Whamm
• Name: WAS protein homolog associated with actin, golgi membranes and microtubules
• ID: MGI:2142282

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0071933	Arp2/3 complex binding	ISO	J:164563
Molecular Function	GO:0071933	Arp2/3 complex binding	IBA	J:265628
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	ISO	J:164563
Cellular Component	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Biological Process	GO:0007015	actin filament organization	ISO	J:164563
Biological Process	GO:0090527	actin filament reorganization	ISO	J:164563
Biological Process	GO:0034314	Arp2/3 complex-mediated actin nucleation	IBA	J:265628
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ISO	J:164563
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	J:212803
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA	J:265628
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:164563
Biological Process	GO:0030032	lamellipodium assembly	ISO	J:164563
Biological Process	GO:0097320	plasma membrane tubulation	ISO	J:164563
Biological Process	GO:0051127	positive regulation of actin nucleation	ISO	J:164563