GO Annotations Graph

• Symbol: Exoc8
• Name: exocyst complex component 8
• ID: MGI:2142527

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:73065
Molecular Function	GO:0031267	small GTPase binding	ISO	J:73065
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0000145	exocyst	ISO	J:164563
Cellular Component	GO:0000145	exocyst	ISO	J:155856
Cellular Component	GO:0000145	exocyst	NAS	J:320331
Cellular Component	GO:0000145	exocyst	IBA	J:265628
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2316351
Biological Process	GO:0007032	endosome organization	ISO	J:164563
Biological Process	GO:0006887	exocytosis	ISO	J:73065
Biological Process	GO:0022617	extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0006893	Golgi to plasma membrane transport	IBA	J:265628
Biological Process	GO:0090148	membrane fission	NAS	J:320331
Biological Process	GO:0000281	mitotic cytokinesis	NAS	J:320331
Biological Process	GO:0008104	protein localization	ISO	J:155856
Biological Process	GO:0008104	protein localization	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0006904	vesicle docking involved in exocytosis	NAS	J:320331
Biological Process	GO:0090522	vesicle tethering involved in exocytosis	NAS	J:320331