Traf3ip2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Traf3ip2
TRAF3 interacting protein 2
MGI:2143599

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:304178
Molecular Function	GO:0005515	protein binding	IPI	J:282433
Molecular Function	GO:0005515	protein binding	IPI	J:176465
Molecular Function	GO:0005515	protein binding	IPI	J:250338
Molecular Function	GO:0005515	protein binding	IPI	J:282433
Molecular Function	GO:0005515	protein binding	IPI	J:176465
Molecular Function	GO:0005515	protein binding	IPI	J:144320
Molecular Function	GO:0005515	protein binding	IPI	J:144319
Molecular Function	GO:0005515	protein binding	IPI	J:282433
Molecular Function	GO:0005515	protein binding	IPI	J:176466
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:161934
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:260559
Cellular Component	GO:0031410	cytoplasmic vesicle	IPI	J:282433
Cellular Component	GO:0005634	nucleus	IPI	J:282433
Biological Process	GO:0002344	B cell affinity maturation	IMP	J:161592
Biological Process	GO:0001783	B cell apoptotic process	IMP	J:93923
Biological Process	GO:0001782	B cell homeostasis	IMP	J:161592
Biological Process	GO:0019724	B cell mediated immunity	IGI	J:138560
Biological Process	GO:0019724	B cell mediated immunity	IGI	J:138560
Biological Process	GO:0023035	CD40 signaling pathway	IGI	J:138560
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:179229
Biological Process	GO:0097398	cellular response to interleukin-17	IDA	J:282433
Biological Process	GO:0002367	cytokine production involved in immune response	IMP	J:179229
Biological Process	GO:0002534	cytokine production involved in inflammatory response	IMP	J:179229
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:144320
Biological Process	GO:1990959	eosinophil homeostasis	IMP	J:144319
Biological Process	GO:0002447	eosinophil mediated immunity	IMP	J:144320
Biological Process	GO:0001768	establishment of T cell polarity	IMP	J:179229
Biological Process	GO:0010467	gene expression	IMP	J:260559
Biological Process	GO:0010467	gene expression	IMP	J:179229
Biological Process	GO:0010467	gene expression	IMP	J:144319
Biological Process	GO:0010467	gene expression	IMP	J:144320
Biological Process	GO:0010467	gene expression	IDA	J:250338
Biological Process	GO:0010467	gene expression	IMP	J:176466
Biological Process	GO:0007507	heart development	IDA	J:236924
Biological Process	GO:0006959	humoral immune response	IBA	J:265628
Biological Process	GO:0006959	humoral immune response	IMP	J:93923
Biological Process	GO:0006955	immune response	IMP	J:203923
Biological Process	GO:0006955	immune response	IMP	J:162859
Biological Process	GO:0006955	immune response	IMP	J:176466
Biological Process	GO:0002377	immunoglobulin production	IGI	J:138560
Biological Process	GO:0002377	immunoglobulin production	IGI	J:138560
Biological Process	GO:0002377	immunoglobulin production	IMP	J:187766
Biological Process	GO:0002377	immunoglobulin production	IMP	J:179229
Biological Process	GO:0002377	immunoglobulin production	IMP	J:93923
Biological Process	GO:0006954	inflammatory response	IMP	J:144319
Biological Process	GO:0006954	inflammatory response	IMP	J:118670
Biological Process	GO:0006954	inflammatory response	IMP	J:158905
Biological Process	GO:0006954	inflammatory response	ISO	J:118670
Biological Process	GO:0006954	inflammatory response	IMP	J:179229
Biological Process	GO:0006954	inflammatory response	IDA	J:118670
Biological Process	GO:0006954	inflammatory response	IMP	J:138560
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IMP	J:162859
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IMP	J:144319
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IDA	J:176466
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IDA	J:176465
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IDA	J:260559
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IDA	J:250338
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IMP	J:203923
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IMP	J:158905
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	IMP	J:260559
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	IMP	J:144320
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	ISO	J:118670
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	IDA	J:118670
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	IMP	J:118670
Biological Process	GO:0001822	kidney development	IMP	J:187766
Biological Process	GO:0002269	leukocyte activation involved in inflammatory response	IMP	J:158905
Biological Process	GO:0048535	lymph node development	IMP	J:187766
Biological Process	GO:0048255	mRNA stabilization	IMP	J:176465
Biological Process	GO:0048255	mRNA stabilization	IDA	J:152025
Biological Process	GO:0070254	mucus secretion	IMP	J:144320
Biological Process	GO:0042119	neutrophil activation	IMP	J:144319
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0006606	protein import into nucleus	IDA	J:250338
Biological Process	GO:0070534	protein K63-linked ubiquitination	ISO	J:164563
Biological Process	GO:0034504	protein localization to nucleus	IDA	J:282433
Biological Process	GO:0110012	protein localization to P-body	IDA	J:282433
Biological Process	GO:0000209	protein polyubiquitination	IMP	J:260559
Biological Process	GO:0016567	protein ubiquitination	IMP	J:188557
Biological Process	GO:0034097	response to cytokine	IMP	J:144319
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:144320
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:176465
Biological Process	GO:0043588	skin development	IMP	J:162859
Biological Process	GO:0048536	spleen development	IMP	J:187766
Biological Process	GO:0042110	T cell activation	IMP	J:158905
Biological Process	GO:0030217	T cell differentiation	IMP	J:187766
Biological Process	GO:0072538	T-helper 17 type immune response	IDA	J:250338
Biological Process	GO:0002334	transitional two stage B cell differentiation	IMP	J:161592
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	IGI	J:138560
Biological Process	GO:0042092	type 2 immune response	IMP	J:179229

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24